Aim of the
study supported by the Campania Oncoterapie project is to improve available
treatments for oncological patients using strategies tailored to the specific
characteristics of each single patient.
During the
last decade, an evolutionary step has been achieved in the medical science-omic sciences improved tremendously our ability to obtain large dataset of
data with sustainable costs (high throughput screening). Today, clinical
practice is based on limited amount of biomarkers used as target, nonetheless,
even these superficial screening improved the clinicians ability of to choose
the most efficient therapies.
Progress
in oncology allowed improved pharmacological efficiency together with mass
screening that allows identifying neoplastic lesions at early time point when
success chances are much higher.
We now aim
to move forward and better discriminate between tumors. Using an “high quality
picture” approach we will identify the specific characteristics of patients and
tumors allowing the clinician to proceed with the optimal therapy
available. Furthermore, we aim to use
the recently developed 3D cell culture techniques to perform pharmacological
studies to identify new and more efficient molecules.